empiric antibiotics
# Skin/soft tissue
@eileen_hasse
# PO options
- staph:
- doxy
- linezolid
- clinda (diarrhea, often high levels of resistance)
- bactrim
- strep:
- keflex (true q6h dosing)
- cefadroxil (BID)
- amoxicillin
- augmentin (“amoxicillin plus diarrhea”)
# UTI
Don’t treat UA w/o sx, unless pregnant or prior to urologic procedure. Symptomatic sterile pyuria: can challenge with abx or wait and watch.
# PO options
- nitrofurantoin
- bactrim
- augmentin
- cefdinir (3rd gen)
- fosfomycin (one time dose, covers ESBL, expensive)
- don’t need a fluoroquinolone unless pyelo o/p tx (e.g. young female who is doing ok w PO intake)
# PNA
- strep pneumo, H flu, moraxella, legionella, mycoplasma, staph, PsA
# PO options
- azithromycin + something
- amox
- augmentin
- FQ
# IV options
- CAP: azithromycin + CTX
- HAP: vanc + cefe, vanc + zosyn
- think about MRSA nares, though can have nares -ve/trachea +ve
# Meningitis
- n meningitidis, strep pneumo (MCC), H flu, listeria (>50yo, immunocompromised)
- HSV
# IV options
- vanc (s pneumo is sometimes resistant to CTX, not for MRSA)
- CTX
- +/- ampicillin (listeria)
- +/- acyclovir (HSV)
- dexamethasone
# course
7-21 days, depending on the bug